Infantile Cortical Hyperostosis

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Abstract
THE syndrome that has become known as infantile cortical hyperostosis, after the suggestion of Caffey and Silverman,1 is characterized by the usually sudden onset of swelling of the face, thorax or extremities, hyperirritability, fever, fluctuating course and roentgenographic evidence of periosteal new-bone formation. Probably the first case was described by Roske,2 but the syndrome was not appreciated until the publication of the descriptions of the clinical and roentgenologic picture.1 , 3 , 4 There are now over 60 cases in the literature. Sherman and Hellyer5 reviewed their x-ray films taken of infants during the preceding twenty years and found no case of infantile cortical . . .

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