SERUM URIC ACID IN UNITED STATES AND BRAZILIAN MILITARY RECRUITS, WITH A NOTE ON ABO BLOOD GROUPS1

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Abstract
Florey, C. du V. and R. M. Acheson (Yale Univ. Schl. of Medicine, 60 College St., New Haven, Conn. 06510). Serum uric acid in United States and Brazilian military recruits, with a note on ABO blood groups. Amer. J. Epid. 1968, 88: 178–188. The frequency distributions of serum uric acid for 2, 085 U.S. and 1, 990 Brazilian military recruits were similar in shape, except for a small right-hand tail present only in the U.S. data, and were more or less symmetrical but not Gaussian. The. U.S. mean level was 0.82 mg% higher than the Brazilian mean, a statistically significant difference. The relationship between serum uric acid (SUA) and age, height, weight and ponderal index was investigated using multiple regression analysis techniques. Weight was the most highly correlated with SUA, but even when all four independent variables were included in the analysis, they accounted for only 5.6% and 1.8% of the SUA variation in the U.S. and Brazilian data respectively. The usefulness of the regression equation is discussed. A statistically significantly lower SUA was found in Brazilians of blood group AB. This was not observed in the U.S. data nor has it been reported in other populations so it is uncertain whether the finding has biological significance. It is concluded that the differences between the two countries are probably of environmental origin, although the reasons for these differences are obscure.

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