Abstract
Tuberculosis takes an enormous toll on humankind. The impact of Mycobacterium tuberculosis has not been weakened despite the availability of effective antituberculosis agents. Industrialized countries recorded a net decline in the incidence of tuberculosis during the 20th century, but, unfortunately, developing countries continue to witness the spread of this disease at a frightening and increasing pace. On the verge of the 21st century, ã8 million people globally were newly infected with M. tuberculosis, 95% of them in developing countries, and 2 million deaths resulted from uncontained infections per year. Thus, tuberculosis remains a leading killer [1].