The utilization of inorganic sulphate by granulation tissue
- 1 March 1957
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 65 (3) , 550-554
- https://doi.org/10.1042/bj0650550
Abstract
The QO2 and SO42- uptake of guinea-pig granulation-tissue slices decreased with the maturation of the tissue after tendonec -tomy. The SO42- uptake by granulation tissue was stimulated by addition of glucose (2 x 10-2[image]) or pyruvate (2 x 10-2[image]), and was completely inhibited, together with QO2, by fluoroacetate (2 x 10-2[image]). Sulfate uptake by the tissue was also inhibited by gentisate and phenol. Phenol acted as an alternative substrate and was shown by chromatog-rapny to be converted into phenyl sulfate, which itself was an inhibitor of S35O42- uptake by granulation tissue.Keywords
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