Urinary Excretion of Oxalate in Renal Failure

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Abstract
The daily urinary excretion of oxalate was lower than normal in patients with renal failure; the decrease was directly proportional to the impairment of renal function. The gut flora from uremic patients destroys oxalate in vitro more efficiently than the gut flora from normal people. Apparently, an adaptation occurs in the gut flora of uremics to metabolize oxalate, and this enteric elimination may account for its decreased urinary excretion.

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