Discontinuation of Use and Switching of Antidepressants

Abstract
Guidelines issued by the Agency for Health Care Policy and Research and the American Psychiatric Association recommend continued treatment with antidepressants for at least 4 to 9 months after depressive symptoms resolve to prevent relapse.1-3 Despite these guidelines, rates of treatment discontinuation within 3 months after the start of treatment can reach 68%, depending on the type of antidepressant prescribed and the population studied.4-10

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