Effect of Ranitidine on Meal-Induced Gastric Pepsin and Acid Secretion and the Influence of Adding Ethanol to the Meal
- 1 January 1986
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Gastroenterology
- Vol. 21 (1) , 123-128
- https://doi.org/10.3109/00365528609034635
Abstract
The effect of rantidine on meal-stimulated pepsin and acid secretion 3-4 h after administration of the drug was compared in 10 healthy volunteers. The results showed an insignificant reduction of pepsin output, whereas acid output was reduced 78.5%, demonstrating the difference in response of the chief and parietal cells to an H2-receptor antagonist. Adding ethanol to the meal did not reduce the acid-inhibiting effect of ranitidine.This publication has 17 references indexed in Scilit:
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