Different Distribution of HIV Type 1 Genetic Variants in European Patients with Distinct Risk Practices
- 10 February 2000
- journal article
- Published by Mary Ann Liebert Inc in AIDS Research and Human Retroviruses
- Vol. 16 (3) , 299-304
- https://doi.org/10.1089/088922200309403
Abstract
The use of two genetic markers has permitted the analysis of the distribution of two different human immunodeficiency virus type 1 (HIV-1) variants in patients of the homosexual (HO) and intravenous drug user (IDU) groups in distinct European countries. In Germany, Holland, and Italy the variants circulating in each risk group of HO and IDU patients were genetically distinguishable according to the genetic markers used. In contrast, in France and Spain, the same variant has been recovered from patients with different risk practices. These data highlight the diversity of the HIV-1 epidemic in Europe and the different patterns of HIV-1 variant distribution in European countriesKeywords
This publication has 9 references indexed in Scilit:
- HIV Type 1 Sequences with GGC Substitution in Injecting Drug Users in GreeceAIDS Research and Human Retroviruses, 1999
- Evidence for HIV Type 1 Strains of U.S. Intravenous Drug Users as Founders of AIDS Epidemic among Intravenous Drug Users in Northern EuropeAIDS Research and Human Retroviruses, 1996
- Global burden of the HIV pandemicThe Lancet, 1996
- Sequence Note: env Gene Diversity of HIV Type 1 Isolates from SpainAIDS Research and Human Retroviruses, 1996
- Consistent risk group-associated differences in human immunodeficiency virus type 1 vpr, vpu and V3 sequences despite independent evolutionJournal of General Virology, 1996
- CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choiceNucleic Acids Research, 1994
- Silent Mutation Pattern in V3 Sequences Distinguishes Virus according to Risk Group in EuropeAIDS Research and Human Retroviruses, 1994
- Increasing antigenic and genetic diversity of the V3 variable domain of the human immunodeficiency virus envelope protein in the course of the AIDS epidemic.Proceedings of the National Academy of Sciences, 1993
- Complete nucleotide sequence of the AIDS virus, HTLV-IIINature, 1985