MYOCARDIAL TRANSFER OF SODIUM AND POTASSIUM: EFFECT OF ACETYL STROPHANTHIDIN IN NORMAL DOGS 12
Open Access
- 1 November 1956
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 35 (11) , 1220-1228
- https://doi.org/10.1172/jci103377
Abstract
The cardiac arterio-venous difference of Na and K were used as a measure of their myocardial exchange after rapid infusion of strophanthidin in 8 intact anesthetized dogs. There was an abrupt rise in coronary venous K and concurrent fall in Na. The net exchange indicated a larger uptake of Na, than release of K by the myocardium. Control values were regained after 30 minutes. A decline in stroke work of the left ventricle occurred, possibly related to the ionic changes.Keywords
This publication has 23 references indexed in Scilit:
- Biochemical Characteristics of Glycerol Extracted Myocardial FibersAmerican Journal of Physiology-Legacy Content, 1955
- Action of 3-Acetyl-Strophanthidin in Isolated Mammalian Heart.Experimental Biology and Medicine, 1953
- Passage of Molecules Through Capillary WallsPhysiological Reviews, 1953
- AN EVALUATION OF THE MEASUREMENT OF THE CARDIAC OUTPUT AND OF THE SO-CALLED PULMONARY BLOOD VOLUME BY THE DYE-DILUTION METHOD1953
- EFFECT OF OUABAIN ON ACTOMYOSIN THREADS1953
- Effect of Strophanthus on Coronary Blood Flow and Cardiac Oxygen Consumption of Normal and Failing Human HeartsCirculation, 1950
- Action of Cardiac Glycosides on the Polymerization of ActinNature, 1949
- THE EFFECTS OF THE CARDIAC GLYCOSIDES UPON THE DYNAMICS OF THE CIRCULATION IN CONGESTIVE HEART FAILURE. I. OUABAIN 12Journal of Clinical Investigation, 1948
- STUDIES IN CONGESTIVE HEART FAILUREJournal of Clinical Investigation, 1931
- THE EFFECT OF DIGITALIS ON THE CARDIAC OUT-PUT OF DOGS AND ITS BEARING ON THE ACTION OF THE DRUG IN HEART DISEASEJournal of Clinical Investigation, 1926