Establishment of a Human Small Cell Lung Cancer Cell Line Producing a Large Amount of Anti-diuretic Hormone
- 1 July 1994
- journal article
- case report
- Published by Wiley in Japanese Journal of Cancer Research
- Vol. 85 (7) , 718-722
- https://doi.org/10.1111/j.1349-7006.1994.tb02420.x
Abstract
A new cancer cell line (Lu‐165) producing a large amount of anti‐diuretic hormone (ADH, 2.8 μg/g protein) was established from a 50‐year‐old small cell lung cancer patient presenting with a syndrome of inappropriate anti‐diuretic hormone secretion. These cells grew well in serum‐supplemented medium and during more than 100 passages they continued producing a large amount of this hormone. This cell line will be a useful tool for studies of the biochemistry and pathology of ADH‐producing cancer.Keywords
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