Base-specific ribonucleases potentially involved in heterogeneous nuclear RNA processing and poly(A) metabolism
- 4 June 1984
- journal article
- Published by Wiley in FEBS Letters
- Vol. 171 (1) , 25-30
- https://doi.org/10.1016/0014-5793(84)80453-6
Abstract
Polyadenylation and splicing of heterogeneous nuclear RNA, two crucial steps in mRNA processing, are apparently enzymically mediated processes. This contribution summarizes the properties and the presumed functions of the known poly(A) catabolic enzymes (endoribonuclease IV and V, 2′,3′-exoribonuclease) as well as those of the pyrimidine-specific endoribonucleases associated with snRNP—hnRNP complexes (endoribonuclease VII, acidic pI 4.1 endoribonuclease and poly(U)-specific U1 snRNP-nuclease).Keywords
This publication has 46 references indexed in Scilit:
- Association of a polyuridylate‐specific endoribonuclease with small nuclear ribonucleo‐proteins which had been isolated by affinity chromatography using antibodies from a patient with systemic lupus erythematosusEuropean Journal of Biochemistry, 1983
- RNA synthesis in isolated nucleiJournal of Molecular Biology, 1982
- Phosphorylation and activation of poly(A)‐endoribonuclease from calf thymus glandFEBS Letters, 1982
- hnRNP from HeLa cells contain a ribonuclease active on double-stranded RNABiochemical and Biophysical Research Communications, 1979
- A correlation between the rate of poly(A) shortening and half-life of messenger RNA in adenovirus transformed cellsJournal of Molecular Biology, 1978
- Control of Enzymic Hydrolysis of Polyadenylate Segment of Messenger RNA: Role of Polyadenylate‐Associated ProteinsEuropean Journal of Biochemistry, 1978
- Cell-free translation analysis of messenger RNA in echinoderm and amphibian early developmentDevelopmental Biology, 1977
- Endoribonuclease IV. 2. Further Investigation on the SpecificityEuropean Journal of Biochemistry, 1976
- 3′ Non-coding region sequences in eukaryotic messenger RNANature, 1976
- Synthesis and turnover of nuclear and cytoplasmic polyadenylic acid in mouse L cellsJournal of Molecular Biology, 1974