The elusive meningococcal meningitis serogroup: a systematic review of serogroup B epidemiology
Open Access
- 17 June 2010
- journal article
- review article
- Published by Springer Nature in BMC Infectious Diseases
- Vol. 10 (1) , 175
- https://doi.org/10.1186/1471-2334-10-175
Abstract
Invasive meningococcal disease (IMD), is a widely distributed, complex human disease affecting all age categories. The causative agent, Neisseria meningitidis, is spread through aerosol respiratory droplets. 13 different serogroups have been identified, each with varying epidemiological features including prevalence, virulence, immunogenicity, geographical and temporal distribution. Although preventative measures are available for several of the serogroups, meningococcal disease caused by serogroup B is of particular interest due to the challenge it presents concerning vaccine development.Keywords
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