INFLUENCE OF DIETARY FACTORS ON HYPERTENSION INDUCED BY CHOLINE DEFICIENCY

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Abstract
It has been confirmed that one week of choline deficiency at weaning age results in systemic hypertension in rats maintained on stock rations, thereafter. When such rats were transferred to synthetic diets low in either protein or salt, systolic pressures fell to essentially normal levels within 3 weeks. The blood pressure of rats on low-protein or low-salt rations could be maintained moderately elevated if they were fed unusually large amts. of salt or protein, respectively.