STUDIES ON THE ADDUCTS OF SULFUR DIOXIDE WITH VITAMIN D

Abstract
Vitamin D2 reacted rapidly with liquid sulfur dioxide at the Δ5,10(19)-diene part to give the α and the β-face adducts in about 1:1 ratio. Both adducts extruded sulfur dioxide by thermolysis to give 5,6-trans vitamin D2 in good yield together with a trace of vitamin D2. Similar reactions were examined for vitamin D3 and trans vitamin D2.
Keywords