PROGRESSIVE FACIAL HEMIATROPHY: III. REPORT OF A CASE, WITH OTHER SIGNS OF DISEASE OF THE CENTRAL NERVOUS SYSTEM

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Abstract
In this, the third case report of progressive facial hemiatrophy, the syndrome which on first inspection seemed to be limited to the face was again found to be diffuse. It has been pointed out1 that progressive facial hemiatrophy may be associated with convulsions, scleroderma and many forms of autonomic imbalance, such as anisocoria, disturbances in growth, visceral sensation, emotions (lability and depression) and fat metabolism. The best explanation for the apparently unrelated and fortuitous collection of signs is that the facial changes, as well as the other alterations in the tissues and in metabolism, result from lesions in the vegetative apparatus of the diencephalon or brain stem. REPORT OF CASE The following case is additional evidence for this hypothesis: History.—A housewife, aged 30, entered the outpatient department of the Boston City Hospital in June, 1927, complaining of generalized aches and pains, especially in the right arm and leg,

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