Selection of Controls in Case-Control Studies: III. Design Options
- 1 May 1992
- journal article
- research article
- Published by Oxford University Press (OUP) in American Journal of Epidemiology
- Vol. 135 (9) , 1042-1050
- https://doi.org/10.1093/oxfordjournals.aje.a116398
Abstract
Several design options available in the planning stage of case-control studies are examined. Topics covered include matching, control/case ratio, choice of nested case-control or case-cohort design, two-stage sampling, and other methods that can be used for control selection. The effect of potential problems in obtaining comparable accuracy of exposure is also examined. A discussion of the difficulty in meeting the principles of study base, deconfounding, and comparable accuracy (S. Wacholder et al. Am J Epidemiol 1992; 135: 1019–28) in a single study completes this series of papers. Am J Epidemiol 1992; 135: 1042–50Keywords
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