Increased Expression in Erythrocytic Ii Antigens in Sickle Cell Disease and Sickle Cell Trait
- 30 June 1977
- journal article
- research article
- Published by Wiley in Vox Sanguinis
- Vol. 33 (1) , 29-36
- https://doi.org/10.1111/j.1423-0410.1977.tb02233.x
Abstract
The reactivity of human erythrocytes with anti-I and anti-i sera was estimated in 36 normal adults, 18 individuals with sickle cell anemia and 27 individuals with sickle cell trait by quantitative hemagglutination with a sensitive autoanalyzer system. SS erythrocytes showed significantly increased I and i reactivity when compared to normal erythrocytes. AS erythrocytes demonstrated some increase in Ii reactivity. No correlation was found between erythrocytic HbF [fetal Hb] content and i reactivity.Keywords
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