ACUTE COCAINE INTOXICATION

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Abstract
Intoxications resulting from the use of cocaine are observed very frequently by rhinologists, who are still dependent on this drug to secure a satisfactory intranasal anesthesia. A committee appointed by the Council on Pharmacy and Chemistry to investigate the subject found that a large number of the fatalities and other disastrous sequelae were not reported in the literature. They found further that a large number of the ill results were seen even in instances in which only small amounts of dilute solutions of the alkaloid had been used. Syncope and even death resulting from the use of cocaine were not at all uncommon, especially during the earlier period when it was used by injection. The urge for a drug having the anesthetic qualities of cocaine but not its toxicity has caused a number of newer anesthetics to be elaborated, none of which have been able to duplicate its ready adsorbability

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