Potent Inhibition of NFAT Activation and T Cell Cytokine Production by Novel Low Molecular Weight Pyrazole Compounds

This publication has 34 references indexed in Scilit:

• TRANSCRIPTION FACTORS OF THE NFAT FAMILY:Regulation and Function
  Annual Review of Immunology, 1997
• Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppression
  Nature, 1996
• The Mechanism of Action of Cyclosporin A and FK506
  Clinical Immunology and Immunopathology, 1996
• Crystal structures of human calcineurin and the human FKBP12–FK506–calcineurin complex
  Nature, 1995
• Direct Demonstration of NFATp Dephosphorylation and Nuclear Localization in Activated HT-2 Cells Using a Specific NFATp Polyclonal Antibody
  Journal of Biological Chemistry, 1995
• NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes
  Immunology Today, 1994
• The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun
  Nature, 1993
• The immunosuppressive and toxic effects of FK-506 are mechanistically related: pharmacology of a novel antagonist of FK-506 and rapamycin.
  The Journal of Experimental Medicine, 1992
• Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
  Cell, 1991
• Is cyclophilin involved in the immunosuppressive and nephrotoxic mechanism of action of cyclosporin A?
  The Journal of Experimental Medicine, 1991