More About: Tumor Angiogenesis as a Prognostic Assay for Invasive Ductal Breast Carcinoma

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Abstract
Axelsson et al. (1) reported in this Journal that microvessel density (MVD) in 220 breast cancers did not provide prognostic information for metastasis-free or overall survival; this result was contrary to most published series (2). The study was designed to assess the reliability of MVD to predict the outcome for patients with breast cancer. MVD was measured by two observers who independently selected and scored the three most vascular fields. The maximum MVD was used for survival analysis (1).