The additivity of substituent effects in one-bond13C–1H coupling constants in polysubstituted pyridines

Abstract
The additivity of substituent effects upon one-bond 13C–1H coupling constants in polysubstituted pyridines is described. The substituent effects on 1J(13CH) in monosubstituted pyridines account very well for 1J(13CH) in a variety of polysubstituted pyridines. The additivity relation has some diagnostic value in the assignment of 13C resonances where the chemical shift difference is extremely small.

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