IMMUNE-COMPLEXES IN WUCHERERIA-BANCROFTI INFECTION IN MAN
- 1 January 1982
- journal article
- research article
- Vol. 60 (6) , 919-+
Abstract
The levels of immune complexes in the sera of patients with W. bancrofti infection were determined by enzyme-linked immunosorbent assay, using a rabbit antibody to the adult Setaria digitata antigens SD2-4, and by the [complement component] Clq-binding assay. Of microfilaremic subjects .apprx. 3-7% and of amicrofilaremic symptomatic patients, 30-40% had levels of immune complexes that were significantly higher than the levels observed in nonfilarial control subjects. The antigen in the polyethylene glycol-precipitated immune complexes was isolated. This W. bancrofti antigen was similar to the S. digitata antigen SD2-4. Both antigens had the properties of an acidic glycoprotein of isoelectric point .apprx. pH 3.This publication has 15 references indexed in Scilit:
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