Inflammation in healing. 1. Time-course and mediation of exudation in wound healing in the rat.

  • 1 June 1969
    • journal article
    • Vol. 50  (3) , 309-18
Abstract
The time-course of increased vascular permeability in excised wounds in the skin of the rat was measured by injecting Evan's blue i.v. at various times after wounding and extracting the dye which exuded into the injured tissues during various short intervals of time. A single peak of increased permeability occurred within the first hour after which exudation rapidly diminished to a low level which then persisted for at least 5 days after wounding.