Microbial resolution and asymmetric reduction related to optically active 1,3-diphenylpropane-1,3-diol
- 1 January 1987
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 5,p. 334-335
- https://doi.org/10.1039/c39870000334
Abstract
An efficient microbial resolution of 1,3-diphenylpropane-1,3-diol (4) has been achieved by exposing the corresponding diacetate to Trichoderma viride; a reductive cleavage of chiral acetals (6) derived from (4) with hydride reagent (Br2AlH, Cl2AlH) affords optically active alcohols (8) of high enantiomeric purities.Keywords
This publication has 0 references indexed in Scilit: