PORCINE MALIGNANT HYPERTHERMIA. I: METABOLIC AND PHYSIOLOGICAL CHANGES

Open Access

1 April 1976

journal article
research article
Published by Elsevier in British Journal of Anaesthesia

Vol. 48 (4) , 297-304
https://doi.org/10.1093/bja/48.4.297

Abstract

Porcine malignant hypothermia was studied in seven Retrain pigs under standardized experimental conditions. In five animals malignant hyperthermia was triggered with suxamethonium and halothane, but in two pigs suxamethonium alone was used. Characteristic metabolic and physiological changes were found and these are discussed with regard to a possible mechanism to explain the malignant nature of the syndrome.

Keywords

FAMILY SUIDAE
MALIGNANT HYPERTHERMIA DUE TO ANESTHESIA
SUCCINYLCHOLINE
HYPOTHERMIA
NATURAL
INDUCED
HALOTHANE
ABSTRACT SUMMARIES

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