Neurometabolic effects of an inborn error of amino acid metabolism demonstrated in vivo by 1H NMR
- 1 February 1986
- journal article
- research article
- Published by Wiley in Magnetic Resonance in Medicine
- Vol. 3 (1) , 150-156
- https://doi.org/10.1002/mrm.1910030123
Abstract
The elevated levels of brain histidine in histidinaemic mice are detected in vivo by 1H NMR at 8.5 and 1.9 T. The concentrations determined from the in vivo spectra correlate well with subsequent analytical determinations. This technique is discussed in relation to monitoring phenylalaninc in humans with phenylketonuria. © 1986 Academic Press, Inc.This publication has 12 references indexed in Scilit:
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