Measurement of plasma nortriptyline concentrations: radioimmunoassay and gas-chromatography compared.
- 1 November 1978
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Chemistry
- Vol. 24 (11) , 2023-2025
- https://doi.org/10.1093/clinchem/24.11.2023
Abstract
We compared measurement of plasma nortriptyline by a recently developed radioimmunoassay technique with values obtained by traditional gas chromatography. The coefficient of correlation (r) was 0.98 for 84 samples from 21 controlled patients; for a separate series of 45 samples from 34 patients who were receiving in addition other medication, r was 0.96. Use of radioimmunoassay in the routine determination of plasma nortriptyline concentration is discussed.This publication has 4 references indexed in Scilit:
- A radioimmunoassay for nortriptyline (and other tricyclic antidepressants) in plasma.Clinical Chemistry, 1978
- Radioimmunoassay for flupenthixol in plasma.Clinical Chemistry, 1977
- Nortriptyline plasma levels and therapeutic responseClinical Pharmacology & Therapeutics, 1976
- Amitriptyline plasma levels and therapeutic responseClinical Pharmacology & Therapeutics, 1976