Two initiation sites for adenovirus 5.5S RNA
- 1 January 1978
- journal article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 5 (1) , 195-204
- https://doi.org/10.1093/nar/5.1.195
Abstract
Adenovirus specific 5.5S RNA is heterogeneous at its 5' terminus. Complete pancreatic RNase digests of the RNA reveal a 5' terminal oligonucleotide (pp)pApGpCp in addition to the major 5' terminal (pp)pGpGpGpCp (1). Both 5' termini are detected early as well as late after adenovirus infection. In isolated nuclei, alpha-amanitin inhibits all 5.5S RNA transcription at a concentration of 200 microgram/ml, indicating that both initiation sites are recognized by RNA polymerase III.Keywords
This publication has 16 references indexed in Scilit:
- Studies on synthesis and structure of virus-coded low molecular weight RNA in adenovirus type 2-infected KB cellsVirology, 1976
- A new species of virus-coded low molecular weight RNA from cells infected with adenovirus type 2Cell, 1976
- Low molecular weight viral RNAs transcribed by RNA polymerase III during adenovirus 2 infectionCell, 1976
- Synthesis of Complementary RNA Sequences During Productive Adenovirus InfectionProceedings of the National Academy of Sciences, 1974
- Correction for non-uniform phosphate labeling of E. coli and phage RNAs synthesized in vivoBiochemical and Biophysical Research Communications, 1973
- Preparation, molecular weight, base composition, and secondary structure of giant nuclear ribonucleic acidBiochemistry, 1973
- Isolation and Characterization of Adenovirus Messenger Ribonucleic Acid in Productive InfectionJournal of Virology, 1972
- A distinct RNA polymerase activity, synthesizing 5.5 s, 5 s and 4 s RNA in nuclei from adenovirus 2-infected HeLa cellsJournal of Molecular Biology, 1972
- The Nucleotide Sequence of a Low Molecular Weight Ribonucleic Acid from Cells Infected with Adenovirus 2Journal of Biological Chemistry, 1971
- A two-dimensional fractionation procedure for radioactive nucleotidesJournal of Molecular Biology, 1965