The relationship of ileal outflow to colonic propulsion

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Abstract
Ing conditions was nearly five times as common as that of a moderate outflow in diarrheic subjects. The ileal outflow was increased to some degree after lunch in two-thirds of all subjects, whatever their bowel function might have been, and this was attributed to a gastroileal reflex; it was three times more likely to be augmented by a large amount after ingestion of food when it had already been excessive before the meal. Colonic propulsion averaged about 7.5 cm per hour in subjects who had fewer than two motions per day, and 30 cm per hour in those who had more frequent motions, and had been given lunch. During the hour after lunch the upper limit of colonic propulsion that was consistent with normal bowel function was about 22 cm per hour (approximately three times the resting level). About one-fourth of the diarrheic patients who had moderate ileal outflow at rest, and in whom there may have been primary colonic hyperactivity, showed propulsion of 30 cm per hour even under resting conditions. Among the subjects with excessive ileal outflow while at rest, an increased frequency of motions in the absence of gastrointestinal disease appeared to be chiefly due to overactivity of the gastroileal and gastrocolic reflexes. In those with disease of the gastrointestinal tract, diarrhea was most often associated with evidence of malabsorption, but it still appeared to depend on the same reflex mechanism. © The ASCRS 1969...