The CD4–Th1 model for multiple sclerosis: a crucial re-appraisal
- 1 March 2004
- journal article
- review article
- Published by Elsevier in Trends in Immunology
- Vol. 25 (3) , 132-137
- https://doi.org/10.1016/j.it.2004.01.007
Abstract
No abstract availableKeywords
This publication has 52 references indexed in Scilit:
- The enigma of multiple sclerosis: inflammation and neurodegeneration cause heterogeneous dysfunction and damageCurrent Opinion in Neurology, 2003
- T Cell Response in Experimental Autoimmune Encephalomyelitis (EAE): Role of Self and Cross-Reactive Antigens in Shaping, Tuning, and Regulating the Autopathogenic T Cell RepertoireAnnual Review of Immunology, 2002
- Mac-1+ myelopoiesis induced by CFA: a clue to the paradoxical effects of IFN-γ in autoimmune disease modelsTrends in Immunology, 2001
- Failure to Suppress the Expansion of the Activated Cd4 T Cell Population in Interferon γ–Deficient Mice Leads to Exacerbation of Experimental Autoimmune EncephalomyelitisThe Journal of Experimental Medicine, 2000
- Activated Human T Cells, B Cells, and Monocytes Produce Brain-derived Neurotrophic Factor In Vitro and in Inflammatory Brain Lesions: A Neuroprotective Role of Inflammation?The Journal of Experimental Medicine, 1999
- Axonal Transection in the Lesions of Multiple SclerosisNew England Journal of Medicine, 1998
- Myelin Basic Protein–specific T Helper 2 (Th2) Cells Cause Experimental Autoimmune Encephalomyelitis in Immunodeficient Hosts Rather than Protect Them from the DiseaseThe Journal of Experimental Medicine, 1997
- High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic miceCell, 1994
- Selection for T-cell receptor Vβ–Dβ–Jβ gene rearrangements with specificity for a myelin basic protein peptide in brain lesions of multiple sclerosisNature, 1993
- Effect of anti-interferon-γ and anti-interleukin-2 monoclonal antibody treatment on the development of actively and passively induced experimental allergic encephalomyelitis in the SJL/J mouseJournal of Neuroimmunology, 1992