Biliary excretion of copper in LEC rat after introduction of copper transporting P‐type ATPase, ATP7B
Open Access
- 1 April 1999
- journal article
- Published by Wiley in FEBS Letters
- Vol. 448 (1) , 53-56
- https://doi.org/10.1016/s0014-5793(99)00319-1
Abstract
Wilson's disease, an autosomal recessive disorder, is characterized by the excessive accumulation of hepatic copper that results from reduced biliary copper excretion and disturbed incorporation of c...Keywords
This publication has 19 references indexed in Scilit:
- ATP7B (WND) proteinThe International Journal of Biochemistry & Cell Biology, 1998
- Identification and Analysis of Mutations in the Wilson Disease Gene (ATP7B): Population Frequencies, Genotype-Phenotype Correlation, and Functional AnalysesAmerican Journal of Human Genetics, 1997
- N-terminal Domains of Human Copper-transporting Adenosine Triphosphatases (the Wilson's and Menkes Disease Proteins) Bind Copper Selectively in Vivo and in Vitro with Stoichiometry of One Copper Per Metal-binding RepeatPublished by Elsevier ,1997
- Organization of P-type ATPases: significance of structural diversityBiochemistry, 1995
- Copper incorporation into ceruloplasmin in rat liversBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1995
- The LEC rat has a deletion in the copper transporting ATPase gene homologous to the Wilson disease geneNature Genetics, 1994
- Expression of the Wilson disease gene is deficient in the Long-Evans Cinnamon ratBiochemical Journal, 1994
- Impaired Hepatic Copper Homeostasis in Long-Evans Cinnamon Rats: Reduced Biliary Excretion of CopperPediatric Research, 1994
- Biliary Copper Excretion in Acutely and Chronically Copper-loaded RatsHepatology, 1993
- Biliary copper excretion by hepatocyte lysosomes in the rat. Major excretory pathway in experimental copper overload.Journal of Clinical Investigation, 1989