Immunofluorescence studies in reactional leprosy with relevance to treatment
- 1 January 1978
- journal article
- research article
- Published by Springer Nature in Archives of Dermatological Research
- Vol. 261 (3) , 323-330
- https://doi.org/10.1007/bf00455302
Abstract
Twenty-three biopsies of skin lesions of patients with various types of leprosy, showing a recent reaction, were examined by means of immunofluorescence (IF) methods. The patients were divided into two groups according to the number of inflammatory cells, staining with various FTC-labelled antiimmunoglobulin antisera, in representative areas of the biopsies. It was found that the presence of these cells was correlated with a good response to thalidomide treatment. Dreiundzwanzig Hautbiopsien von Patienten mit verschiedenen Lepraformen, die eine rezente Reaktion zeigten, wurden mittels der Immunofluorescenz (IF)-Technik untersucht. Die Patienten konnten in zwei Gruppen verteilt werden, abhängig von der Zahl der Entzündungszellen in repräsentativen Biopsiegebiete, die fluorescierenden mit FTC-gekoppelte Anti-Immunoglobulin-Antisera. Es zeigte sich eine positive Korrelation dieser Zellen bei einer erfolgreichen Thalidomidbehandlung.This publication has 33 references indexed in Scilit:
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