Local macrophage and myofibroblast proliferation in progressive renal injury in the rat remnant kidney.
Open Access
- 1 August 1998
- journal article
- research article
- Published by Oxford University Press (OUP) in Nephrology Dialysis Transplantation
- Vol. 13 (8) , 1967-1974
- https://doi.org/10.1093/ndt/13.8.1967
Abstract
We have recently shown that blockade of angiotensin II activity inhibits local macrophage and myofibroblast proliferation in progressive non-immune renal injury in the rat remnant kidney. However, it is not known whether this local proliferation contributes to macrophage and myofibroblast accumulation and the development of renal injury. Therefore, we examined this issue in a detailed time-course study of the rat remnant kidney.Keywords
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