POST-RESECTION STAGE GROUPING IN CARCINOMA OF LUNG

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  • 1 January 1977
    • journal article
    • research article
    • Vol. 145  (5) , 725-728
Abstract
The postsurgical treatment classification and staging system for carcinoma of the lung were evaluated in 403 patients admitted to a completed prospective randomized adjuvant cancer chemotherapy trial conducted by the Veterans Administration Surgical Adjuvant Group. The proposed TNM [tumor, node, metastasis] classification suggested by the American Joint Committee for Cancer Staging and End Results Reporting is supported. Stage grouping as suggested by the Committee fails to separate adequately the various prognostic groups. This appears to be better accomplished by stage grouping modification suggested by the Radiation Therapy Oncology Group. In the latter scheme, the 5 yr survival rate of patients with postsurgical treatment stage I disease is 40.9%; stage II, 26.2% and stage III, 10.5%. In the Joint Committee classification, these survival rates are 30.8, 25.5 and 10.5%, respectively. Eighteen patients with undifferentiated small cell carcinoma were also evaluated. The long term survival of 3 of 6 patients with small peripheral lesions without metastatic lymph node involvement supports the opinion that resection of these specific lesions continues to be the treatment of choice.

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