FACTORS AFFECTING THE DEVELOPMENT OF SERUM IMMUNOGLOBULIN LEVELS IN INFANTS

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Abstract
The humoral immunological status of the newborn is recognized as a combination of (1) immune globulin G derived from the mother and (2) competence for developing active immunity. To these current concepts, the data in the present study add indications that the level of transplacentally acquired IgG may play a role in controlling the time of onset of the infant's own IgG production. Increases of IgG levels occurred much later in infants born with normal adult levels of serum IgG than in infants born with relatively low serum IgG concentrations.

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