Factors Identified as Precipitating Hospital Admissions for Heart Failure and Clinical OutcomesFindings From OPTIMIZE-HF

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Abstract
Heart failure (HF) is the leading cause of hospitalization among US adults older than 65 years, and these hospitalizations contribute substantially to the high costs of the disease. There are 3.6 million hospitalizations with HF as the primary or a secondary cause each year in the United States.1,2 Hospitalizations for HF are also associated with substantial morbidity and mortality; the likelihood of death and rehospitalization is considerably greater than for a comparable period of chronic but stable HF.3,4 Understanding precipitants that contribute to exacerbations of HF and lead to HF admissions, particularly those that are avoidable, is of great importance to clinicians and could favorably influence HF disease management.

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