Entamoeba histolytica -Secreted Products Degrade Colonic Mucin Oligosaccharides
Open Access
- 1 June 2005
- journal article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 73 (6) , 3790-3793
- https://doi.org/10.1128/iai.73.6.3790-3793.2005
Abstract
Degradation of the mucus layer by Entamoeba histolytica is a prerequisite for invasion of the colonic mucosa. In this study, we demonstrate that amoeba-secreted products degrade 3 H-labeled and native colonic mucin oligosaccharides independently of proteolytic activity. We conclude that E. histolytica degrades mucin oligosaccharides, which may facilitate parasite invasion of the colon.Keywords
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