Doxycycline Therapy for Leptospirosis
- 1 May 1984
- journal article
- clinical trial
- Published by American College of Physicians in Annals of Internal Medicine
- Vol. 100 (5) , 696-698
- https://doi.org/10.7326/0003-4819-100-5-696
Abstract
To study antibiotic efficacy, 29 patients with leptospirosis were treated in a randomized, double-blinded fashion with doxycycline, 100 mg orally twice a day, or placebo. Therapy was given for 7 days in a hospital, and patients were followed for 3 weeks afterwards. Duration of illness before therapy and severity of illness were the same in both groups. Doxycycline reduced the duration of illness by 2 days and favorably affected fever, malaise, headache, and myalgias. Treatment prevented leptospiruria and had no adverse effects. Doxycycline is effective in therapy for patients with leptospirosis.Keywords
This publication has 0 references indexed in Scilit: