Diphtheria Antitoxin Levels in US Blood and Plasma Donors
Open Access
- 1 June 1996
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Infectious Diseases
- Vol. 173 (6) , 1493-1497
- https://doi.org/10.1093/infdis/173.6.1493
Abstract
Plasma samples from 500 blood donors were titrated for diphtheria antitoxin (OAT) by the toxin neutralization (TN) test. Only 1.6% of donors had r = .80), there was no correlation (r = .07) for samples with antitoxin titers <0.1 IU/mL, the level of special interest for serosurveys for protection. Titration of 62 immune globulin samples (prepared from 1957 to 1994) showed that OAT levels in Massachusetts blood donors increased concurrently with increased use of tetanus-diphtheria vaccine in the state.Keywords
This publication has 0 references indexed in Scilit: