Thrombolysis with low dose tissue plasminogen activator.
Open Access
- 1 December 1992
- journal article
- case report
- Published by BMJ in Archives of Disease in Childhood
- Vol. 67 (12) , 1483-1484
- https://doi.org/10.1136/adc.67.12.1483
Abstract
Two cases of vena caval thrombosis in infants were successfully treated with low dose (0.01-0.05 mg/kg/hour) local infusions of tissue plasminogen activator after conventional anticoagulant treatment had been unsuccessful. This approach is useful for clots associated with indwelling intravascular catheters, and a low dose infusion of tissue plasminogen activator as a regional application is recommended to achieve clot lysis with minimal systemic effects.Keywords
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