ASSESSMENT OF RISK OF HUMAN INFECTION IN THE MICROBIOLOGICAL LABORATORY

Abstract
In estimating the risk of human infection during research in the microbiological laboratory and in deciding upon appropriate safeguards, it is useful to know the nature of the work in terms of (1) potential accidental microbial aerosol formation and accidental injection, ingestion, cut, and bite; (2) the number of recorded laboratory infections and their outcome; (3) the medical prophylactic procedures available; (4) whether the microorganism is excreted in urine and feces; and (5) whether inoculated animals infect normal cagemate control animals. Detailed tabular summaries with 700 references and working assumptions pertinent to these matters are presented for 162 causative agents or diseases.

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