MENINGO-ENCEPHALITIS DUE TO BRUCELLOSIS WITH THE REPORT OF A CASE IN WHICH B. ABORTUS WAS RECOVERED FROM THE CEREBROSPINAL FLUID, AND A REVIEW OF THE LITERATURE

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Abstract
The signs, symptoms, and significant laboratory fingings as they evolved during a 3-yr. period in a 39-yr.-old male suffering from meningo-encephalitis due to Brucella abortus are described in detail. Similar data from 47 previously reported cases presenting this manifestation of brucellosis were tabulated and reviewed. As in other forms of brucellosis a tendency to remissions and exacerbations and spontaneous recovery was noted. The protean character of the neurologic picture implies that the diagnosis will rest largely on an index of suspicion in cases of meningo-encephalitis in which some other diagnosis has not been firmly established. The pathology appears to be primarily vascular and predominantly meningeal. The diagnosis should be confirmed either by recovery of the organism from the cerebrospinal fluid or the demonstration of a high titer of agglutinins in the blood or cerebrospinal fluid. A specific, reliable form of treatment has yet to be established.

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