Antigenic and genetic analyses of influenza type B viruses isolated in Russia, 1987–91
- 1 October 1993
- journal article
- research article
- Published by Cambridge University Press (CUP) in Epidemiology and Infection
- Vol. 111 (3) , 539-546
- https://doi.org/10.1017/s0950268800057265
Abstract
Summary Four influenza type B viruses isolated in Russia during periods of relatively low (1987–8) or high (1990–1) influenza B activity were characterized antigenically using a microneutralization assay. These isolates were antigenically similar to contemporary reference strains from either of two separate lineages represented by B/Victoria/2/87 and B/Yamagata/16/88. The evolutionary relationships of the variable portion of the haemagglutinin (HA1) genes of these viruses were determined by comparison with influenza B HA1 sequences previously obtained. The Isolate B/USSR/2/87, collected during the 1987–8 influenza season, was found to be closely related to viruses on the B/Victoria/2/87 lineage that circulated during the 1988–9 influenza season in the United States. Sequence analysis of the isolates from the 1990–1 influenza season demonstrated co-circulation of viruses from both the B/Victoria/2/87 and B/Yamagata/16/88 lineages in Russia, confirming the antigenic analysis.Keywords
This publication has 15 references indexed in Scilit:
- Cocirculation of two distinct evolutionary lineages of influenza type B virus since 1983Published by Elsevier ,2004
- Antigenic and Genetic Characterization of the Haemagglutinins of Recent Cocirculating Strains of Influenza B VirusJournal of General Virology, 1992
- Evolution of influenza B/Victoria/2/87-like viruses: occurrence of a genetically conserved virus under conditions of low epidemic activityJournal of General Virology, 1992
- The hemagglutinin of influenza B virus present in clinical material is a single species identical to that of mammalian cell-grown virusVirology, 1990
- Cross-protection against Microvariants of Influenza Virus Type B by Vaccinia Viruses Expressing Haemagglutinins from Egg- or MDCK Cell-derived Subpopulations of Influenza Virus Type B/England/222/82Journal of General Virology, 1989
- The antigenic structure of the influenza B virus hemagglutinin: Operational and topological mapping with monoclonal antibodiesVirology, 1985
- Alterations in the hemagglutinin associated with adaptation of influenza B virus to growth in eggsVirology, 1985
- Antigenic structure of the hemagglutinin of influenza virus B/Hong Kong/8/73 as determined from gene sequence analysis of variants selected with monoclonal antibodiesVirology, 1984
- Evidence for host-cell selection of influenza virus antigenic variantsNature, 1983
- Analysis of Antigenic Drift in the Haemagglutinin Molecule of Influenza B Virus with Monoclonal AntibodiesJournal of General Virology, 1981