Inclusion of Vitamin D2 in β-Cyclodextrin. Evaluation of Different Complexation Methods
- 1 January 1993
- journal article
- research article
- Published by Taylor & Francis in Drug Development and Industrial Pharmacy
- Vol. 19 (8) , 875-885
- https://doi.org/10.3109/03639049309062988
Abstract
Evaluation of inclusion complexation of vitamin D2 with β-cyclodextrin in aqueous solution and solid state was performed by Phase Solubility Diagramm, HPLC, DSC, X-RAY Diffractometry, NMR. Solid inclusion complexes were prepared by spray-drying, kneading and solid dispersion. The dissolution profiles of the complex either in powder or in tablets were studied in order to select the best inclusion processKeywords
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