DEVELOPMENTAL EFFECTS ON LIVER d-GLUCURONOLACTONE DEHYDROGENASE LEVELS AND ON d-GLUCARIC ACID EXCRETION IN URINE; HORMONAL EFFECTS ON d-GLUCARIC ACID EXCRETION IN URINE

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Abstract
SUMMARY Total urinary d-glucaric acid excretion increased with age and weight gain in males and was found to be low in terms of unit body weight in the newborn. In premature infants, there was a direct relationship between the serum bilirubin level and urinary d-glucaric acid excretion. In women excretion was not found to vary with the menstrual cycle, but was increased during prolonged therapy with contraceptive agents.