SO-CALLED MALIGNANT HYPERTENSION
- 1 July 1930
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of internal medicine (1908)
- Vol. 46 (1) , 75-104
- https://doi.org/10.1001/archinte.1930.00140130078007
Abstract
Recent work in America and abroad has emphasized the importance of a group of rapidly fatal cases associated with excessive hypertension. Among the various terms that have been employed to define this condition those most commonly used are "malignant hypertension," "malignant renal sclerosis of Fahr," "genuine contracted kidney" and "chronic interstitial nephritis." The term "malignant hypertension" was first used by Volhard and Fahr1to designate cases of renal arteriosclerosis in which renal failure later developed. They assumed that the condition was caused by the addition of an inflammatory process to a kidney already damaged by arteriosclerosis, leading to infarction and necrosis of the glomerular loops. Fahr2later introduced the anatomic expression "malignant renal sclerosis" to designate changes in the kidney characterized by necrosis of the afferent glomerular arterioles and the capillary loops, with inflammatory changes in the corresponding glomerulus. Keith, Wagener and Kernohan3employed the term "malignant hypertension" in aThis publication has 0 references indexed in Scilit: