Metronidazole in prevention and treatment of bacteroides infections after appendicectomy.
- 7 February 1976
- Vol. 1 (6005) , 318-321
- https://doi.org/10.1136/bmj.1.6005.318
Abstract
The frequency of non-clostridial anaerobic infection was studied in 95 patients who had undergone acute appendicectomy: 49 received prophylactic metronidazole and 46 received placebo. Anaerobic infection did not develop in any of the metronidazole-treated patients, but infections did develop in nine (19%) of the 46 controls. Metronidazole is conveniently administered by suppository to patients who cannot take oral drugs. Five patients with intra-abdominal infections caused by non-clostridial anaerobes were successfully treated with metronidazole.Keywords
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