MYOCARDIAL PROTECTION DURING ISCHEMIC CARDIAC-ARREST - IMPORTANCE OF MAGNESIUM IN CARDIOPLEGIC INFUSATES

  • 1 January 1978
    • journal article
    • research article
    • Vol. 75  (6) , 877-885
Abstract
The increasing use of coronary infusates for the protection of the human heart during ischemic cardiac arrest has placed great emphasis on the need for a rational and safe formulation of any infusion solution. Using a rat heart model of cardiopulmonary bypass and ischemic cardiac arrest, Mg proved to be a highly effective component of protective infusates which can be additive to hypothermia and other protective agents. The concentration of Mg bears a complex relationship to the degree of protection, a fact which stresses the need for the establishment of the correct concentration for optimal protection.