Studies on the blood of an MsHe/MSu proposita and her family

Abstract
The serum of a black woman was found to contain a potent alloanti-N that reacted in direct agglutination tests with the N antigen carried on Ss-active sialoglycoprotein. Thus far, such antibodies were observed only in the sera of MSu/MSu individuals. The proposita had red cells that lacked N. Her blood type was M+, N-, S-, s+, U+, He+. Evidently, she is of the genotype MsHe/HSu. The findings are consistent with recently reported data on the structure of the Henshaw antigen, which is located on a Ss-active sialoglycoprotein that does not carry N.