Endoscopic Management of Cerebrospinal Fluid Rhinorrhea
- 1 October 2004
- journal article
- research article
- Published by Wiley in The Laryngoscope
- Vol. 114 (10) , 1833-1837
- https://doi.org/10.1097/00005537-200410000-00029
Abstract
Purpose: Most anterior skull base defects causing cerebrospinal fluid (CSF) rhinorrhea can be readily approached using endoscopic techniques when surgical repair is necessary. We present our data from endoscopic repair of CSF rhinorrhea with long‐term follow‐up.Methods: Retrospective data analysis of patients that were diagnosed with anterior skull base CSF rhinorrhea and underwent endoscopic repair at a tertiary institution. Data were analyzed to determine the etiology and location of CSF leaks. Diagnostic techniques, surgical techniques, and surgical outcomes were reviewed.Results: Ninety‐two patients were diagnosed with CSF rhinorrhea and underwent endoscopic repair over a 12‐year period. Forty‐eight were males, and 44 were females. The average age was 49 (range 6–81) years. Average follow‐up was 25 months, with a range of 12 to 82 months. The etiology of CSF leak was prior endoscopic sinus surgery in 23 patients (25%), idiopathic in 19 (21%), neurosurgery in 17 (18%), trauma in 18 (20%), and the presence of meningocele/encephalocele in 11 patients (12%). The most common location of the defect was the sphenoid sinus (n = 36, 39%), followed by ethmoid roof (n‐27, 29%), and cribriform plate (n = 24, 26%). Endoscopic repair was initially successful in 78 (85%) patients. Seven additional patients underwent successful revision endoscopic repair for an overall success rate of 92% (n = 85). Five (6%) large skull base defects were eventually repaired by neurosurgery using open intracranial techniques. No major complications were encountered.Conclusion: The intranasal endoscopic approach is an effective and safe technique in the surgical management of anterior skull base CSF rhinorrhea. Long‐term success rate in our patient population was 92%.Keywords
This publication has 41 references indexed in Scilit:
- Transnasal Endoscopic Closure of Cerebrospinal Fluid LeaksThe Laryngoscope, 2003
- Predictive Values of β-Trace Protein (Prostaglandin D Synthase) by Use of Laser-Nephelometry Assay for the Identification of Cerebrospinal FluidNeurosurgery, 2002
- Optimum imaging and diagnosis of cerebrospinal fluid rhinorrhoeaThe Journal of Laryngology & Otology, 2000
- Transnasal Endoscopic Repair of Cranionasal Fistulae: A Refined Technique With Long‐term Follow‐upThe Laryngoscope, 1996
- Composite mucochondral flap for repair of cerebrospinal fluid leaksHead & Neck, 1995
- Das Dach des vorderen Siebbeines: Ein Locus minoris resistentiae an der Schädelbasis*Laryngo-Rhino-Otologie, 1988
- Spectrum of complications in the use of intrathecal fluoresceinJournal of Neurosurgery, 1978
- Cerebrospinal Fluid Fistula: Clinical Aspects, Techniques of Localization, and Methods of ClosureJournal of Neurosurgery, 1969
- Method for the identification and localization of cerebrospinal fluid, rhinorrhea and otorrheaThe Laryngoscope, 1960
- THE LOCALISATION OF CEREBROSPINAL-FLUID FISTULÆThe Lancet, 1956